A chemistry student worked as part of a team to study DNA Extraction and Regeneration of Tylosema exculentum and Tylosema fassoglensis.
A team of chemistry students investigated an efficient synthetic route of Isoptilocaulin which has been shown to have medicinal properties making it a formidable antibiotic against both gram negative and gram positive bacteria. It has also been shown to be an effective chemotherapeutic agent against leukemia cells in vitro.
A student explored a novel chelation method for removing metal contaminants like arsenic and lead from water supplies.
Work from current year:
Research Presentations at Professional Meetings of the American Chemical Society (ACS)
Six undergraduate research students (Zeenat Razvi, Julia Bair, Nooria Razai, Sally Yacout, Meredith Hyatt, and Brittney Mitchell) attended and presented April 8-12, 2013 at the 245th National American Chemical Society Meeting in New Orleans, LA. The following list includes all citations from Meredith (Meredith students/faculty are bold):
“Science of art: From creation to authentication to preservation” Dr. Kassy A. Mies and Sayyeda Zeenat Razvi
“Reductive mechanism of iron release from the iron-siderophore, ferrioxamine B, by NaDH in the presence of the iron(II) chelator, TPEN,” Dr. Kassy A. Mies and Sayyeda Zeenat Razvi
“Investigation of the roles of several iron(II) chelators in the relese of iron from ferrioxamine B via reduction by NADH,” Julia Bair and Dr. Kassy A. Mies
“FbpA: A continuum between bacterial transferring and periplasmic binding protein,” Dr. Claire J Parker Siburt, Dr. Sambuddha Banerjee, D. Aruna Weerasinghe, Dr. Timothy A. Mietzner, and Dr. Alvin L. Crumbliss
“Efficient synthetic route to isopitlocaulin utilizing an intramolecular Diels-Alder reaction,” Dr. William A. Dupont, Devin E. Montague, Nooria Razai, and Sally M. Yacout
“Probing Diels-Alder adducts of anthracene and maleimide as mechanically active functional groups,” Meredith G. Hyatt, Zachary S. Kean, Bobin Lee, and Professor Stephen L. Craig
“Metal coordination polymer networks of iron(II) and ruthenium(II) tris(bipyridine),” Kristina M. Vaillonis, Mallory, M. McVannel, Meredith G. Hyatt, Marian L. Pippin, and Dr. Al D. Schwab
“Spatial variation of organic volatile compounds associated with gas production operations in southwestern Pennsylvania,” Brittney L. Mitchell, Brandon Miller, Robert Swarthout, Dr. Yong Zhou, and Dr. Barkley C Sive
“Hydrocarbon emissions associated with hydraulic fracturing in northeastern Colorado and southwestern Pennsylvania: A lot of fracking gas,” Barkley C. Sive, Robert Swarthout, Brandon Miller, Brittney Mitchell, Emily Horsman, Rachel Russo, and Yong Zhou
Work from last academic year:
Razvi, S, Folk, D, & Franz, K. (2011, September). Hydrophobic and Hydrophilic Copper Chelators: Pro-oxidants or Anti-oxidants? Poster session presented at the 125th North Carolina American Chemical Society Sectional Meeting, Raleigh, NC.
“Metal coordination polymer networks: A modular approach,” Meredith G. Hyatt, Miriam L. Pippin, and Alexander D. Schwab; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
“Examination of the beta-amyloid peptide and its copper complexes using spectroscopic methods,” Michelle D. Maiden and Kassy A. Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
“Examination of the binding of iron(III) to the amyloid-beta peptide and its potential implications in Alzheimer’s disease,” Sarah S. Murray and Kassy Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
“Investigation of the interaction between zinc and the beta amyloid peptide,” Rodda A. Ouma and Kassy Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
“Hydrophilic and hydrophobic copper chelators: Pro-oxidants or anti-oxidants?" Sayyeda Zeenat A. Razvi, Drew S. Folk and Katherine J. Franz; 243rd National Meeting of the ACS, San Diego, CA, March 2012.